Synthesis And Characterization ( Oxazepine , Thiazine and Quinazoline ) Derivatives And Study The Biological Activity As Antibacterial

This research. Included the preparation. and characterization some novel. Six seven membered Heterocyclic. Compounds ( oxazepine , thiazine quinazoline ) The first step in clode react 2-amino-6- methoxybenzothiazole with 4- amino acetophenone to get Schiff base derivative (1). second (1) 4 -hydroxy schiff (2) last involve Phthalic Maleic Succinic) anhydride .get derivatives (3,4and 5) also with(2-amino benzoic acid) (2-mercaptobenzoic acid (6)and (7) respectively .the physical; properties of prepared; These Compounds. Were Identification (FT-IR) ,(1H-NMR) (13C-NMR) by spectroscopy thene study their biological effect on two types bacteria Staphylococcus aureuses (Gram positive) Escherichia coli Negative)